Suggested doses :
Large joints: 2 to 4 mg
Small joints: to 1 mg
Bursae: 2 to 4 mg
Tendon Sheaths: to 1 mg
Injections may be repeated from once every 3 to 5 days to once every 2 to 3 weeks
-Dose will vary according to the degree of inflammation and the size and location of the affected site.
-Intrasynovial and soft tissue injections should be limited to 1 or 2 sites; frequent intra-articular injections may cause damage to joint tissue.
Use: As adjunctive therapy for an acute episode or exacerbation of synovitis of osteoarthritis, rheumatoid arthritis, acute and subacute bursitis, acute gouty arthritis, epicondylitis, acute nonspecific tenosynovitis, and posttraumatic osteoarthritis.
5mg a day was too much and he was having bad side effects, extreme lethargy, he stopped eating,and drinking and his diarrhea actually got worse. Half a pill ever other day was not enough his stool was normal the first day then back to diarrhea the second. Half a pill mg a day seems to be the formula that works for him. He tolerates it well,and his stool remains normal. Mischief is much more active and healthy now,and is actually gaining weight. I am very pleased. Like I said I think it saved his life. Also the drug is very inexpensive $10 bucks a month
The active ingredient of Efudix is 5-Fluorouracil which is a form of chemotherapy drug. Abnormal (pre-cancerous or cancer) cells will selectively absorb Efudix allowing the drug to kill the abnormal cells. The treatment will produce a skin reaction that typically develops over the first week of treatment with redness and slight scaling. Over the second week the reaction intensifies with increasing redness and crusting with resolution of the reaction occurring several weeks following cessation of treatment. A stronger reaction will be observed in those who have a greater number of abnormal cells in the skin. It is important not to stop the treatment because of the reaction. Efudix is highly effective in treating AKs, particularly when large areas of skin are affected. Repeated treatments may be required and this is perfectly safe.