Synthese hormone steroide

Because steroids are lipophilic, they diffuse easily through the cell membranes, and therefore have a very large distribution volume. In their target tissues, steroids are concentrated by an uptake mechanism which relies on their binding to intracellular proteins (or " receptors ", see below). High concentration of steroids are also found in adipose tissue, although this is not a target for hormone action. In the human male, adipose tissue contains aromatase activity, and seems to be the main source of androgen-derived estrogens found in the circulation. But most of the peripheral metabolism occurs in the liver and to some extent in the kidneys, which are the major sites of hormone inactivation and elimination, or catabolism (see below).

1,25 dihydroxy vitamin D (calcitriol); 1,25(OH)(2)D; 18kDa translocator protein; 3-hydroxy-3-methylglutaryl co-enzyme A; 3β-hydroxysteroid dehydrogenase; 3βHSD; ACAT; ACTH; ANT; CRAC; Cholesterol side chain cleavage; Cholesterol transport; ER; FAD; HDL; HMGCoA; HSL; IMM; IMS; Km; LAL; LDL; LH; MENTAL; MENTHO; MLN64; MLN64 N-terminal; MLN64 N-terminal domain homologue; Michaelis constant; NADPH; NPC; Niemann Pick type C; OMM; Outer mitochondrial membrane; P450scc; PAP7; PBR; PCP; PKA; PKAR1A; PRAX1; PTH; SF1; SOAT; SR-B1; SREBPs; START; StAR; StAR-related lipid transfer domain; Steroidogenesis; Steroidogenic acute regulatory protein; TSPO; TSPO-associated protein 1; TSPO-associated protein 7 (ACBD3); VDAC1; Vitamin D; acyl transferase; adenine nucleotide transporter; adrenocorticotropic hormone; cholesterol recognition amino acid consensus domain; endoplasmic reticulum; flavin adenine dinucleotide; high density lipoproteis; hormone-sensitive neutral lipase; inner mitochondrial membrane; intramembranous space; low-density lipoproteins; luteinizing hormone; lysosomal acid lipase; metastatic lymph node clone 64; mitochondrial cytochrome P450 specific for cholesterol side-chain cleavage; nicotinamide adenine dinucleotide phosphate; outer mitochondrial membrane; parathyroid hormone; peripheral benzodiazepine receptor; phosphate carrier protein; protein kinase A; protein kinase A regulatory subunit 1α; scavenger receptor B1; steroidogenic acute regulatory protein; steroidogenic factor 1; sterol O-acetyltransferase; sterol regulatory element binding proteins; voltage-dependent anion channel

Synthese hormone steroide

synthese hormone steroide


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