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Baeyer- Villiger oxidation is the oxidative cleavage of a carbon-carbon bond adjacent to a carbonyl, which converts ketones to esters and cyclic ketones to lactones [19,20]. The mechanism of this chemical process was originally proposed by Criegee . It involves a two step process: a nucleophillic attack of a carbonyl by a peroxo species resulting in the formation of a 'Criegee' intermediate, which then undergoes rearrangement to the corresponding ester. Commonly used peracids or oxidants include: m-chloroperoxybenzoic acid, hydrogen peroxide, peroxyacetic acid and trifluoroperoxy acetic acid. This chemical process is highly significant, because the products generated are compounds which are intermediates in the synthesis of natural products or bioactive compounds. However, the oxidants used in chemical Baeyer- Villiger oxidation (BVO) are expensive and hazardous and also the reaction generates a large amount of waste products . Hence biological (or enzymatic) BVO offers a 'greener' approach for the production of chiral lactones.