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Used in traditional Chinese medicine for over 5,000 years, ephedra has a number of pros. The Chinese have used it mainly to treat asthma and colds. In Western medicine, ephedrine and pseudoephedrine, derivatives of ephedra, are used to treat low blood pressure, and congestion associated with colds and flu, respectively.
Ephedra is also used as a dietary supplement. It has both thermogenic and stimulant properties. Thermogenesis means that the body heats up due to an increase in metabolism. This helps the body to burn extra calories.
Another of ephedra’s pros is that it increases the breakdown of fatty tissue. This means that the body uses more fat as energy. It’s also believed that ephedra suppresses appetite and can help to boost and maintain energy levels, possibly leading to improved athletic performance.
In weight loss products, ephedra is often combined with caffeine as the combination seems to boost the effect of both compounds.
Despite all of ephedra’s pros, some still believe it can be dangerous, as there have been a number of reported side effects. However, if used sensibly and in moderation it’s believed by many to be quite safe. Still, as with any weight loss supplement, if you’re thinking of taking a product containing ephedra, it would be a good idea to talk to your doctor first.
Ephedrine is what is called a sympathomimetic amine which is commonly used as an appetite suppressant, to aid focus, energy, and break up decongestion. Derived from the ephedra family of plants you find ephedrine on the market in the form of sulfates or hydrochlorides.
Chinese medicine has been using ma huang for years and ephedrine is a principal ingredient in ma haung.
Ephedrine is made up of a sympathomimetic amine - which means, its primary delivery of process relies on its non-direct function on the adrenergic receptor system, which is an aspect of the sympathetic nervous system (SNS). While ephedrine may lack strong agonist function at a- and ß-adrenergic receptors, the primary delivery is to unlock norepinephrine from stored vesicles in the presynaptic neurons. The unlocked norepinephrine is sent into the neuronal synapse where it is works to engage the postsynaptic adrenergic receptors.
Ephedrine was at one time largely used as a nasal decongestant, and as a bronchodilator in the relief of asthma symptoms. It continues to be used for asthma and now is used as a diet pill as well.
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Adequate folate status is critical for maintaining optimal methylation. Folate is essential for DNA and RNA synthesis, neurotransmitter synthesis, and the conversion of homocysteine to methionine, thus supporting healthy homocysteine levels. Methyl CpG has an aggressive 2mg-dose of 5-Methyltetrahydrofolate per capsule, giving your patients the intensive support they need to maximize the methylation cycle.
B12 is considered by many to be the second most important nutrient in balancing homocysteine levels. It is a required co-factor in the conversion of homocysteine to methionine via the folate pathway. Vitamin B12 shortfall is common in the elderly and those consuming vegetarian diets.
Another important ingredient for methylation and homocysteine metabolism, Vitamin B6 is known to maintain balanced homocysteine levels, even amongst those who have previously supplemented folate alone.
Riboflavin has a positive effect on homocysteine metabolism and methylation. Recent studies show that plasma homocysteine is inversely related to riboflavin in subjects with the 677C>T polymorphism. This indicates the importance of riboflavin status for those who have impaired methylation due to 677C>T polymorphisms.
Betaine (Trimethyl glycine)
Betaine (TMG) acts as a strong methyl donor to homocysteine—converting it to methionine. This conversion pathway occurs in the liver and kidney and contributes to optimal homocysteine balance in those patients with impaired methionine metabolism.