Octreotide is an analog of the peptide hormone somatostatin , which inhibits the production of the growth hormone as well as numerous peptide hormones of the gastrointestinal system, including insulin , glucagon , pancreatic polypeptide , gastric inhibitory polypeptide , and gastrin . Octreotide is used for suppression of the hormonal syndromes which accompany several pancreatic islet cell tumors , including the Zollinger-Ellison syndrome of gastrinoma and the chronic hypoglycemia of insulinoma . It is also effective in suppression of the carcinoid syndrome , caused by advanced or extra- gastrointestinal carcinoid tumors. Octreotide may also be used for treatment of severe diarrhea caused by 5-fluorouracil chemotherapy or radiation therapy . 
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