Neural injections of Bromodeoxyuridine (BrdU) were applied to males of both groups to test for neurogenesis . Analysis showed that testosterone and dihydrotestosterone regulated adult hippocampal neurogenesis (AHN). Adult hippocampal neurogenesis was regulated through the androgen receptor in the wild-type male rats, but not in the TMF male rats. To further test the role of activated androgen receptors on AHN, flutamide , an antiandrogen drug that competes with testosterone and dihydrotestosterone for androgen receptors , and dihydrotestosterone were administered to normal male rats. Dihydrotestosterone increased the number of BrdU cells, while flutamide inhibited these cells.
Gynecomastia can easily be controlled with SERM’s and AI’s with AI’s being the most efficient. Many performance athletes however often shy away from these items out of fear of it taking away from their gains. Let’s again be clear, if the anabolic androgenic steroids you are using are of top shelf form and if all other things in your life are of an adequate nature, training, food, rest, etc. then your growth will not be hindered. Further, AI’s can also help with water retention and there’s no question androgenic steroids like testosterone can cause water retention but guess what, so can eating too much so before you blame the steroids maybe you need to look at the way you’re stuffing your face. Eating too much is a sin of many athletes who are trying to grow; the truth is most do not need near the amount of food they believe they do and certainly not near the amount of carbohydrates as these really promote bloating and water weight. Learn to control your diet and you’ll see a lot of this water fear laid to rest.